Bacillary angiomatosis is a systemic illness characterised by lesions similar to those of Kaposi sarcoma in the skin, mucosal surfaces, liver, spleen and other organs. It is caused by bacterial infection with Bartonella quintana and Bartonella henselae (cause of catscratch disease and also known as Rochalimaea henselae).The disease is only rarely seen in healthy immunocompetent people Bacillary angiomatosis (BA) is a form of angiomatosis associated with bacteria of the genus Bartonella Bacillary Angiomatosis. Bacillary angiomatosis is a manifestation of infection by Bartonella henselae in immunocompromised patients. This is the same organism that causes cat-scratch disease in noncompromised patients Bacillary angiomatosis may result in lesions in the skin, under the skin, in bone, or in other organs. Bacillary peliosis causes sores in the liver and spleen Bacillary angiomatosis has occasionally been reported in immunocompetent patients. Bacillary peliosis, a form of peliosis hepatis, is a vascular condition caused by B. hensela e. It is characterized by presence of blood-filled cavities in the liver
. These lesions can form on the outer surface of your skin and can even grow on your internal organs such as your spleen, liver, and mucosal surfaces Angiomatosis describes a condition in which proliferating capillaries develop in a lobular pattern. It is seen in the skin or just under the skin (subdermal), in bones, and in other organs. Peliosis describes a condition in which the vascular system develops blood-filled cavities, usually in the liver but also in other organs Bacillary angiomatosis is a vascular, proliferative form of Bartonella infection that occurs primarily in immunocompromised persons. While the disorder is treatable and curable, it may be life..
PURPOSE: To describe the varied clinical manifestations and imaging findings encountered in bacillary angiomatosis, an infectious complication of the acquired immunodeficiency syndrome (AIDS). MATERIALS AND METHODS: Clinical, imaging, and histopathologic findings in nine men (aged 26-50 years) with AIDS and bacillary angiomatosis were described Bacillary angiomatosis in an immunocompetent child: a case report and review of the literature. Zarraga M, Rosen L, Herschthal D. Am J Dermatopathol, 33(5):513-515, 01 Jul 2011 Cited by: 4 articles | PMID: 21285862. Revie Back to: Image Library | Bartonella henselae/Bacillary Angiomatosis Bartonella henselae/Bacillary angiomatosis: hepatosplenomegaly in peliosis hepatis. Description. A CT scan of the abdomen shows hepatosplenomegaly with numerous low-density hepatic parenchymal lesions in addition to pelvic ascites and pulmonary effusions Hepatic peliosis was once considered as an autoimmune or viral illness. Recently, Bartonella hensela (formally Rochalimea sp.) has been established as the etiologic agent .This organism is a gram-negative Rickettsia-like bacterium that causes bacillary angiomatosis of skin, bone, and lymph nodes in patients with AIDS.When characteristic lesions are seen in the liver or, less commonly, the.
Bacillary angiomatosis can also be an invasive disease. B. henselae or B. quintana can invade and set-up infection in the heart, brain, liver, spleen, larynx, lymph nodes and gastrointestinal tract. There does not have to be a history of exposure to cats Hepatic peliosis. Hepatic peliosis is a rare benign vascular condition characterized by dilatation of sinusoidal blood-filled spaces within the liver. There may be involvement of other organs, most commonly the spleen and bone marrow. It can be seen in a variety of settings and is important as appearances may mimic malignancy In immunocompromised patients, complications include bacillary angiomatosis, peliosis, bacteremia, and endocarditis. B. henselae has been cultured from peliotic liver lesions. Affected patients have prolonged fever and hepatomegaly, which in 75% of cases is accompanied by splenomegaly Bacillary angiomatosis in patients who are also infected with HIV most commonly causes anemia, leukopenia, and CD4 + cell counts of less than 0.2 X 10 9 /L. In a series of 42 patients with bacillary angiomatosis, the average CD4 + cell count was 0.021 X 10 9 /L. A rapid drop in hemoglobin level in the absence of bleeding or hemolysis has been reported in a patient with peliosis and was thought. Bartonella henselae is primarily the causative agent of bacillary angiomatosis, a clinical picture that actually only occurs in immunosuppressed individuals (e.g. AIDS patients). The clinical picture is reminiscent of verruga peruviana, a disease that occurs as a chronic form of the Andean endemic Oroya fever (Bartonella bacilliformis)
B henselae can also infect the liver causing hepatica peliosis, which results in nausea, vomiting, diarrhea, and fever with hepatosplenomegaly. Epidemiology. About 50% of patients with bacillary angiomatosis are infected with B henselae, and the remaining cases are infections caused by B quintana Bacillary peliosis of her liver and spleen, as well as bacillary angiomatosis of liver, spleen, and a lymph node, were found. The bacterial isolates had comparable electrophoretic patterns of outer membrane proteins and of restriction endonuclease—digested DNA, which differed from the respective patterns of R quintana Bacillary angiomatosis is a vascular‐proliferative disorder and has been mostly reported in patients with acquired immune deficiency syndrome . However, it has also been found in patients receiving immunosuppressive agents after bone marrow, renal, cardiac and liver transplants, as well as in immunocompetent patients [ 20 - 24 ] Bacillary angiomatosis is characterized most commonly by multiple blood-red papular skin lesions, but disseminated infection with or without skin involvement also has been described. 36 The causative bacilli can infect liver, lymph nodes, pleura, bronchi, bones, brain, bone marrow, and spleen. Additional manifestations include persistent fever. Bacillary Angiomatosis Infection with Bartonella (formerly known as Rochalimaea ) may manifest as vascular proliferative lesions in patients with HIV infection and other immunocompromised hosts. 66 - 68 Bacillary angiomatosis may affect the liver (called bacillary peliosis hepatis), spleen (bacillary splenitis), and skin
Bacillary Angiomatosis (BA) is a rare manifestation of infection caused by Bartonella species, which leads to vasoproliferative lesions of skin and other organs. Bacillary angiomatosis affects individuals with advanced HIV disease or other immune compromised individuals. There are two conceptually distinc CASE REPORT Cutaneous bacillary angiomatosis due to Bartonella quintana in a renal transplant recipient Jiri Orsag,1 Patrik Flodr,2 Oto Melter,3 Jan Tkadlec,3 Jan Sternbersky,4 Miroslav Hruby,1 Anna Klicova,1 Kamil Zamboch,1 Karel Krejci1 and Josef Zadrazil1 1 Department of Internal Medicine III - Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky. Bacillary angiomatosis may angiomatkse accompanied by disseminated visceral involvement as the one described in the current report 1. Lymphonodes were found in the peripancreatic, perihilar, and retroperitoneal regions, as well as moderate ascites and anbiomatose enlargement of the spleen. Bacillary angiomatosis denomination comes from the. Bacillary angiomatosis is a reactive vascular proliferation caused by Bartonella - a family of gram-negative bacilli (B. henselae, B. quinitana, B. baciliformis, B. elizabethae). The patient usually has compromised immune system (usually a male with AIDS). The image shows capillary-caliber vessels lined by plump endothelium with clear cytoplasm. Treatment. Diagnosis: typical histology. Drug / Dose. Comments. doxycycline. 100 mg bid po. Until improvement (until 2 months) Possible interactions with ARVs, see Drug-drug Interactions between ARVs and Non-ARVs. OR clarithromycin. 500 mg bid po
Medical definition of bacillary angiomatosis: a bacterial disease especially of the skin, subcutaneous tissue, and mucous membranes that occurs in immunocompromised individuals (such as those infected with HIV), is characterized chiefly by red or purplish elevated lesions or scaly nodules, may spread to involve bone and internal organs (such as the liver or spleen) with symptoms including. Bacillary Angiomatosis Sinusoidal Obstruction Syndrome Test your knowledge. Metastatic Liver Cancer. Liver metastases are common in many types of cancer, especially those of the GI tract, breast, lung, and pancreas. Symptoms of early liver metastases may be asymptomatic, and nonspecific symptoms often develop first Bacillary Angiomatosis High Quality Pathology Images of Soft Tissue, Vascular & Lymphatic, Angiomatosis Bacillary Angiomatosis Definition A life-threatening but curable infection that causes an eruption of purple lesions on or under the skin that resemble Kaposi's sarcoma. The infection, which occurs almost exclusively in patients with AIDS, can be a complication of cat-scratch disease. Description Bacillary angiomatosis is a re-emerging bacterial.
Background. Bacillary angiomatosis is a vascular, proliferative form of Bartonella infection that occurs primarily in immunocompromised persons. It was first described in 1983 in a patient infected with the human immunodeficiency virus (HIV).  The disease has since been described in patients following organ transplantation and in other individuals with a weakened immune system, although it. We describe two cases of B. henselae associated diseases in liver transplant recipients who both had contact with cats. The first recipient developed localized skin manifestation of bacillary angiomatosis in association with granulomatous hepatitis. He tested positive for Immunoglubulin G (IgG) antibodies against B. henselae disease may present in a more disseminated form with hepatosplenomegaly or meningoencephalitis, or with bacillary angiomatosis in patients with AIDS. ( Am Fam Physician. 2011;83(2):152-155 resembling a common abscess may also be seen. In addition, bacillary angiomatosis can involve the internal organs including the heart, brain, liver, spleen, bone, larynx, lymph nodes and gastrointestinal tract. The symptoms vary with the organ(s) affected, and may include neurological signs, bone pain, weight loss or symptoms related t peliosis hepatis: A liver enlarged by multiple cavernous blood-filled cysts due to use of OCs and androgenic steroids; PH may be associated with CA and TB; a distinct form-bacillary PH, occurs in AIDS. See Bacillary angiomatosis
Bacillary peliosis hepatis (BPH *) is a disease characterized by a unique lesion composed of blood-filled spaces affecting the liver, caused by infection with small Gram-negative organisms of the genusBartonella.Although recently described in patients infected with human immunodeficiency virus (HIV) type 1, BPH is yet to be reported in transplant recipients CONCLUSION: Bacillary angiomatosis, a treatable infection, should be considered in patients with AIDS, particularly when Kaposi sarcoma is suspected clinically. KW - Acquired immunodeficiency syndrome (AIDS) KW - Angiomatosis, bacillary. KW - Liver, diseases. KW - Lung, diseases. KW - Lymphatic system, disease Bacillary angiomatosis: skin/ln + liver/spleen Sx in immunocompromised. Subacute endocarditis. THIS SET IS OFTEN IN FOLDERS WITH... Viruses of Med Import 1 (Herpes) 26 terms. ty3ler. Viruses. 14 terms. ty3ler. Parasites. 17 terms. ty3ler. Sepsis Bacteria. 12 terms. ty3ler. YOU MIGHT ALSO LIKE..
Angiomatosis, bacillary: A bacterial infection due to a cat scratch most often seen today in people with HIV.The disease characteristically presents with swollen lymph nodes (lymphadenitis), sore throat, fatigue, and fever, chills, sweats, vomiting, loss of appetite, and weight loss.There is usually a little bump (a papule) which may be pus-filled (a pustule) at the site of the scratch Peliosis hepatis (also called hepatic peliosis) is a rare benign disorder causing sinusoidal dilatation and the presence of multiple blood-filled lacunar spaces within the liver .]. Peliosis is a term derived from the Greek pelios, which means dusky or purple, referring to the color of the liver parenchyma with peliosis. Similar blood-filled spaces may be seen in the spleen. Bacillary angiomatosis is a relatively new infection affecting primarily patients with human immunodeficiency virus or others with impaired host defenses. It presents most commonly with multiple red skin lesions, but visceral involvement may also occur, including involvement of the liver and spleen Bacillary angiomatosis is a tion of the agent, B quintana, was accomplished by systemic disease, and cutaneous lesions may be means of polymerase chain reaction (PCR) in the accompanied by brain, bone, lymph node, gastroin- skin specimen (VRZB/CDC, Atlanta)
Bacillary angiomatosis is characterized by angiomas, or small, benign tumors or lesions. While they most often appear on the skin, the angiomas can also affect the brain, bone, bone marrow, gastrointestinal system, liver, lymph nodes, respiratory system, or spleen. The condition is usually painful and can be fatal if not treated We report the immunocytochemical identification of Rochalimaea henselae, a newly recognized fastidious, Gram-negative, Warthin-Starry-positive organism, as the common pathogen in bacillary angiomatosis (BA), bacillary peliosis (BP) of the liver and spleen, and persistent fever with bacteremia in immunocompromised patients Bacillary angiomatosis is a vascular proliferative disease involving the skin (other organs such as the liver, spleen, and lymph nodes may also be involved) and occurs in immunocompromised individuals such as organ transplant recipients and HIV-positive individuals A vascular disease of the LIVER characterized by the occurrence of multiple blood-filled CYSTS or cavities. The cysts are lined with ENDOTHELIAL CELLS; the cavities lined with hepatic parenchymal cells (HEPATOCYTES). Peliosis hepatis has been associated with use of anabolic steroids (ANABOLIC AGENTS) and certain drugs. Concepts Cat scratch disease (felinosis, benign lymphatic drainage, cat scratch disease) is an acute zoonotic infectious disease with a contact and transmissible mechanism of transmission of the pathogen, characterized by lymphadenitis, primary affect in the form of a papula, in some cases - conjunctivitis, angiomatosis and liver damage
The diagnosis of bacillary angiomatosis (BA) can be made by finding the characteristic skin lesions confirmed by histopathologic examination (Figure 1). Biopsy shows angioproliferation and microorganisms stained with Warthin-Starry silver stain (Figure 2). Patients are usually immunocompromised. Although BA is a systemic disease, the cutaneous. The most common manifestation of bacillary angiomatosis is a dermal lesion (Table 1). Three types of lesions are seen: cutaneous papules, subcutaneous nodules, and hyperpigmented plaques, in decreasing order of frequency. Papules are usually red-purple in color and range in size from a few millimeters to several centimeters, often surrounded by a collarette of scale Bacillary peliosis refers to hepatic spindle cell proliferation with small blood vessels and blood filled spaces secondary portal hypertension, liver failure, liver rupture or hepatomegaly Patients may also have liver or Bacillary peliosis may show angiomatosis, with spindle cell process accompanied by blood vessel proliferation. Bacillary Angiomatosis Clinical and Histologic Features, Diagnosis, and Treatment Stephanie L. Cotell, MD, Gary A. Noskin, MD Bacillary angiomatosisis a relatively new infection affectingprimarilypatientswith hu- man immunodeficiencyvirus or others with impairedhost defenses. It presents most commonlywith multiple red skin lesions, but visceral involvement may also occur, includinginvolvement.
Bacillary angiomatosis (BA), a newly recognized disease characterized by cutaneous and subcutaneous vascular lesions containing bacillary organisms visualized by Warthin-Starry silver staining, was described predominantly among HIV-infected patients; liver (peliosis hepatis), and spleen (14. Bacillary angiomatosis, also known as bacillary epithelioid angiomatosis or epithelioid angiomatosis, is an infectious disease that causes the proliferation of small blood vessels in the skin and internal organs. Bartonella henselae and Bartonella quintana can cause the disease 20 Bacillary angiomatosis Tanya N. Basu, Chrystalla Macedo and Richard C.D. Staughton Evidence Levels: A Double-blind study B Clinical trial ≥ 20 subjects C Clinical trial < 20 subjects D Series ≥ 5 subjects E Anecdotal case reports First described in 1983, bacillary angiomatosis (BA) is a vasculoproliferative disorder caused by the bacteria Bartonella henselae and Bartonella quintana. Bacillary Angiomatosis Lymphadenopathy is the inflammation and enlargement of lymph nodes due to underlying Bacillary Angiomatosis, which is caused by a bacteria. Bacillary Angiomatosis is a benign vascular tumor caused by infection with bacteria, namely Bartonella henselea or Bartonella quintana. An angiomatosis is a benign growth of small.
Bacillary Angiomatosis Roberto N. Miranda, MD Key Facts Terminology Nodules of small blood vessels resulting from infection by bacterium Bartonella henselae Etiology/Pathogenesis B. henselae and B. quintana are most common agents isolated from BA Domestic cats are major reservoir for B. henselae; transmitted by fleas from cat to cat Clinical Issues Most affected patients ar The manifestations of bacillary angiomatosis include diverse cutaneous lesions, visceral parenchymal bacillary peliosis of the spleen and liver, and involvement of single or multiple organ systems. The organisms causing BA are R. henselae and R. quintana, and these organisms have now been cultured from the spleen and cutaneous lesions of BA as. A 12-year-old boy presented for treatment of widespread papules and fungating, ulcerating nodules (Fig 1). Seven months before referral, HIV was diagnosed, and he started antiretroviral therapy (ART), with a baseline CD4 count of 76 cells per microliter (5%). Per history, the rash began 1 month after ART initiation and progressively worsened in the 6 months after ART therapy started
Bacillary angiomatosis may be accompanied by disseminated visceral involvement as the one described in the current report1. The tissues involved are bone, brain, lymph nodes, respiratory and gastrointestinal tracts, liver, and spleen1. There may also be fever, anorexia, weight loss, abdominal pain, nausea, vomiting, and diarrhea Bacillary angiomatosis represents a cutaneous and systemic infection caused by Bartonella species, typically described in the past in HIV‑positive patients or associated with immunodeficiencies. More recent case reports had brought into attention the probability that this entity may manifest in otherwise healthy individuals, triggered by trauma and skin burns
Bacillary Angiomatosis (BA) is a benign vascular tumor caused by infection with bacteria, namely Bartonella henselea or Bartonella quintana. This tumor is commonly observed in immunocompromised individuals, such as those with AIDS, and can occur on the skin and mucus membranes Peliosis hepatis is associated with use of hormones (eg, anabolic steroids, oral contraceptives, glucocorticoids), tamoxifen, vinyl chloride, vitamin A, and, particularly in kidney transplant recipients, azathioprine. Peliosis hepatis is usually asymptomatic, but occasionally cysts rupture, resulting in hemorrhage and sometimes causing death Fig. 3—34-year-old man with AIDS and bacillary peliosis. A, Transverse contrast-enhanced CT image shows large ill-defined, hypoattenuating lesion (white arrow) with heterogeneous peripheral enhancement within left liver lobe. Smaller subcapsular hypoattenuating lesion (black arrow) with ring enhancement can also be seen in right liver lobe Angiomatois Chil Infectol ; Bacillary angiomatosis BA is a form of angiomatosis associated with bacteria of the genus Bartonella. The following abdominal ultrasonography showed enlarged liver associated to signs of diffused parenchymal disease without nodules, with normal vessels
Bacillary angiomatosis Most common in immunocompromised patients (eg, HIV) Many organs may be affected - bone marrow, lymph nodes, liver, spleen; Hallmark symptoms - vascular nodules, papules, or tumors with proliferation of new blood vessels (angiogenesis) Lesions, termed epithelioid angiomatosis, resemble Kaposi sarcom Bacillary angiomatosis (BA) is caused by infection with Bartonella henselae or Bartonella quintana, gram-negative rods that stimulate the proliferation and migration of endothelial cells. Trauma from cats, such as cat scratches, bites, or licks, have been associated. BA is primarily seen in human immunodeficiency virus (HIV)-infected. The liver biopsies showed areas of peliosis, where bacilli were observed by Warthin-Starry stain. In one case, techniques of molecular biology allowed the identification of Rochalimaea henselae, pathogen involved in bacillary angiomatosis. This rickettsia has been newly recognized in the United-States, where 17 cases of bacillary peliosis have. Summary A 78‐year‐old man, who suffered from chronic lymphocytic leukaemia and diabetes mellitus, but was human immunodeficiency virus (HIV)‐negative, developed disseminated angiomatous papule's following a cat scratch. Bacillary angiomatosis was diagnosed by light and electron microscopic demonstration of the causative bacteria in the vascular lesions. The lesions resolved completely. Bacillary angiomatosis may angiomwtosis accompanied by disseminated visceral involvement as the one described in the current report 1. There was a problem providing the content you requested The tissues involved are bone, brain, lymph nodes, bacilag and gastrointestinal tracts, liver, and spleen 1
Bacillary Angiomatosis Definition A life-threatening but curable infection that causes an eruption of purple lesions on or under the skin that resemble Kaposi's sarcoma. The infection, which occurs almost exclusively in patients with AIDS, can be a complication of cat-scratch disease. Source for information on Bacillary Angiomatosis: Gale Encyclopedia of Medicine, 3rd ed. dictionary Bacillary angiomatosis is a re-emerging bacterial infection that is identical or closely related to one which commonly afflicted thousands of soldiers during World War I. Today, the disease, caused by two versions of the same bacteria, is linked to homeless AIDS patients and to those afflicted with cat-scratch disease Common symptoms include fever, headaches, fatigue, poor appetite, brain fog, muscle pain, and swollen glands around the head, neck, and arms. Known diseases caused by Bartonella infections include chronic lymphadenopathy, trench fever, chronic bacteraemia, culture-negative endocarditis, bacillary angiomatosis, bacillary peliosis, vasculitis. Bacillary angiomatosis (BA) is a form of angiomatosis associated with bacteria of the genus Bartonella. Bacillary angiomatosis (BA) is a form of angiomatosis associated with bacteria of the genus Bartonella. of the body, such as the brain, bone, bone marrow, lymph nodes, gastrointestinal tract, respiratory tract, spleen, and liver. Symptoms. Histopathological examination of skin lesions by shaving disclosed vascular proliferation of capillaries with typical endothelial cells, accompanied by edema, neutrophils, and basophils packed with clumps of bacilli visible at Grocott stain, consistent with the diagnosis of bacillary angiomatosis. LM2907N DATASHEET PDF
Bacillary angiomatosis is a proliferative vascular disease due to both B. quintana and B. henselae. The disease is characterised by angioproliferative lesions of skin (sarcoma-like skin lesions) or various organs (spleen, liver, bone marrow and lymph nodes)  Vasculoproliferative disorder - cystic, blood filled spaces in the liver, surrounded by fibromyxoid matrix containing inflammatory cells and dilated capillaries. Spaces may merge with hepatic sinuosoids. May be associated with Bartonella henselae infection. Natural host is the cat; Transmitted between cats by flea CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Abstract. This is the first reported case of bacillary angiomatosis associated with Bartonella henselae in Thailand. The clinical, pathological, and microbiological findings are presented. The bacterium was isolated from a biopsy of skin lesions obtained on admission and identified by cellular morphology.
Bartonella species infections, including cat-scratch disease, trench fever, and bacillary angiomatosis--what molecular techniques have revealed. West J Med . 1996 Jan. 164(1):39-41. [Medline] Bacillary angiomatosis: A bacterial infection due to a cat scratch most often seen today in people with HIV.The disease characteristically presents with swollen lymph nodes (lymphadenitis), sore throat, fatigue, and fever, chills, sweats, vomiting, loss of appetite, and weight loss.There is usually a little bump (a papule) which may be pus-filled (a pustule) at the site of the scratch bacillary angiomatosis (BA) and bacillary peliosis (BP) may develop [1, 2]. In contrast, immunocompetent persons rarely develop BA-BP ; they more typically develop granulomatous (cat-scratch disease) and bacteremic disease (trench fever) with- out angioproliferation during infection with B. henselae and B. quintana, respectively 
Peliosis hepatis is a rare vascular condition of the liver characterized by a proliferation of the sinusoidal hepatic capillaries that results in cystic blood-filled cavities distributed randomly throughout the liver . The term originates from the Greek pelios, which means blue/black or discolored extravasated blood Immunocytochemical identification of Rochalimaea henselae in bacillary (epithelioid) angiomatosis, parenchymal bacillary peliosis, and persistent fever with bacteremia
Applicable Clinical Terms Definitions. Angiomatosis: A condition with multiple tumor-like lesions caused either by congenital or developmental malformations of BLOOD VESSELS, or reactive vascular proliferations, such as in bacillary angiomatosis.Angiomatosis is considered non-neoplastic. Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification. Immunocompromised patients with HIV/AIDS may also develop a systemic disease, bacillary angiomatosis, characterized by reddish-brown papular skin lesions mimicking Kaposi sarcoma. Neurologic involvement in the forms of encephalitis, myelitis, retinitis, facial palsy, and peripheral neuritis may also occur in about 2% of patients with B henselae. ^ a b c Bacillary Angiomatosis: Practice Essentials, Background, Pathophysiology. 2017-02-09. Cite journal requires |journal= ^ Koehler JE, Sanchez MA, Garrido CS, et al. (December 1997). Molecular epidemiology of bartonella infections in patients with bacillary angiomatosis-peliosis An investigation of the phylogeny of the causative agent of bacillary angiomatosis using 16S ribosomal RNA sequence and the design of specific nucleic acid probes. 1992. Стилі APA, Harvard, Vancouver, ISO та ін. Drancourt, Michel. Other bacterial diseasesCat-scratch disease